An efficient solid-phase synthesis of substituted benzofuran using selenium-bound resin

作者：Zhang Yin Jun; Wang Yu Guang^*

来源：Applied Organometallic Chemistry, 2012, 26(5): 212-216.

DOI：10.1002/aoc.2840

• polymer-supported selenium resin
• selenium-induced cyclization
• benzofuran
• solid-phase synthesis
• oxidative cleavage

A very efficient solid-phase synthesis of substituted benzofuran using polymer-supported selenium resin is described. The advantages of the new method are good yields, high purity, straightforward operations, broad range and high diversity of products, lack of odor, and good stability of the resins. The easy work-up procedure makes the method suitable for building parallel libraries.

• 出版日期2012-5
• 单位浙江工业大学