An ultrasensitive and low-cost graphene sensor based on layer-by-layer nano self-assembly

作者：Zhang, Bo^*; Cui, Tianhong

来源：Applied Physics Letters, 2011, 98(7): 073116.

DOI：10.1063/1.3557504

• PROSTATE-SPECIFIC ANTIGEN
• CARBON NANOTUBES
• CANCER
• OXIDE
• IMMUNODETECTION
• NANOPARTICLES
• IMMUNOSENSOR
• SYSTEMS
• FILMS

The flexible cancer sensor based on layer-by-layer self-assembled graphene reported in this letter demonstrates features including ultrahigh sensitivity and low cost due to graphene material properties in nature, self-assembly technique, and polyethylene terephthalate substrate. According to the conductance change of self-assembled graphene, the label free and labeled graphene sensors are capable of detecting very low concentrations of prostate specific antigen down to 4 fg/ml (0.11 fM) and 0.4 pg/ml (11 fM), respectively, which are three orders of magnitude lower than carbon nanotube sensors under the same conditions of design, manufacture, and measurement.

• 出版日期2011-2-14