Ameloblastoma: a clinical review and trends in management

作者:McClary Andrew C; West Robert B; McClary Ashley C; Pollack Jonathan R; Fischbein Nancy J; Holsinger Christopher F; Sunwoo John; Colevas A Dimitrios; Sirjani Davud*
来源:European Archives of Oto-Rhino-Laryngology, 2016, 273(7): 1649-1661.
DOI:10.1007/s00405-015-3631-8

摘要

Ameloblastoma is a rare odontogenic neoplasm of the mandible and maxilla, with multiple histologic variants, and high recurrence rates if improperly treated. The current mainstay of treatment is wide local excision with appropriate margins and immediate reconstruction. Here we review the ameloblastoma literature, using the available evidence to highlight the change in management over the past several decades. In addition, we explore the recent molecular characterization of these tumors which may point towards new potential avenues of personalized treatment.

  • 出版日期2016-7