Fe3O4 nanoparticles: As an efficient, green and magnetically reusable catalyst for the one-pot synthesis of 1,8-dioxo-decahydroacridine derivatives under solvent-free conditions

作者：Ghasemzadeh Mohammad Ali; Safaei Ghomi Javad^*; Molaei Halimeh

来源：Comptes Rendus Chimie, 2012, 15(11-12): 969-974.

DOI：10.1016/j.crci.2012.08.010

• Fe3O4
• 1,8-dioxo-decahydroacridine
• Solvent-free
• Multicomponent reactions
• Nanoparticles
• Catalysts

An efficient and environmentally friendly method for the one-pot synthesis of 1,8-dioxo-decahydroacridines has been developed in the presence of Fe3O4 nanoparticles. The multicomponent reactions of aldehydes, dimedone and amines were carried out under solvent-free conditions to obtain some 1,8-dioxo-9-aryl-10-aryl-decahydroacridine derivatives. The present approach provides several advantages including high yields, short reaction times, little catalyst loading and facile catalyst separation.

• 出版日期2012-12