Mad2 %26quot;Opens%26quot; Cdc20 for BubR1 Binding

作者：Caldas Gina V; DeLuca Jennifer G^*

来源：Molecular Cell, 2013, 51(1): 3-4.

DOI：10.1016/j.molcel.2013.06.017

In this issue of Molecular Cell, Han et al. (2013) demonstrate that Mad2 induces a conformational change in Cdc20 that permits BubR1 binding, thereby producing the physiologically relevant APC/(Cdc20) inhibitor.

• 出版日期2013-7-11