A double-blind randomized clinical trial of two carbamide peroxide tooth bleaching agents: 2-year follow-up

作者：Meireles S S; Santos I S; Della Bona A; Demarco F F^*

来源：Journal of Dentistry, 2010, 38(12): 956-963.

DOI：10.1016/j.jdent.2010.08.003

• Carbamide peroxide
• Tooth bleaching
• Clinical trials
• Randomized

Objectives This double blind randomized clinical trial aimed to evaluate the whitening effect of two at home tooth bleaching agents and the effect of dietary habits after 2 years The patients view about bleaching longevity was also investigated
Methods Ninety two subjects with mean shade of C1 or darker for the six maxillary anterior teeth were randomized into two groups (n = 46) according to the carbamide peroxide (CP) concentration 10% (CP10) or 16% (CP16) The treatment was performed using the whitening agent in a tray for 2 h/day during 3 weeks Shade evaluations were done with a shade guide and a spectrophotometer at baseline 1 month 6 month 1 year and 2 year post bleaching
Results Eighty one (88%) of the original 92 subjects enrolled in the study were recalled at 2 year follow up and the tooth shade remained significantly lighter than at baseline in both treatment groups considering the tooth shade median values (p < 0 001) or the color parameters L*a* (p < 0 001) for CP10 and L*b* for CP16 group (p < 0 001) Subjects from CP10 and CP16 reported a consumption of beverage and food stains as high as at 6 month and 1 year recalls and more than 66% of the participants from each group reported a tooth shade relapse from mild to moderate (p = 0 6)
Significance At 2 year post bleaching tooth shade remained lighter than at baseline for both CP concentrations tested To

• 出版日期2010-12