A case of 63,X/64,XX mosaicism in a subfertile pony mare

作者：Pienkowska Schelling A; Handler J; Neuhauser S; Schelling C^*

来源：Schweizer Archiv fur Tierheilkunde, 2016, 158(4): 266-268.

DOI：10.17236/sat00059

• horse
• subfertility
• chromosomal mosaic
• SRY negative
• 63,X/64,XX

The present case report describes a 6-year old subfertile pony mare, which became pregnant after the eleventh artificial insemination. The examination of the ovaries and the uterus did not reveal any abnormal clinical findings and the mare showed a regular oestrous cycle. Based on cytogenetic and molecular genetic analyses it became possible to elucidate the observed subfertility. The mosaic karyotype of the mare consisted of 63,X (20%) and 64,XX (80%) cells. A PCR analysis failed to amplify sequences from the equine SRY gene. The observed classic 63,X/64,XX mosaicism is a plausible explanation for the subfertility of the mare.

• 出版日期2016-4