Allylation and Crotylation of Ketones and Aldehydes Using Potassium Organotrifluoroborate Salts under Lewis Acid and Montmorillonite K10 Catalyzed Conditions

作者：Nowrouzi Farhad; Thadani Avinash N; Batey Robert A^*

来源：Organic Letters, 2009, 11(12): 2631-2634.

DOI：10.1021/ol900599q

Two convenient highly diastereoselective protocols for the allylation and crotylation of ketones using practical, air- and water-stable potassium allyl and crotyltrifluoroborate salts have been developed. BF(3)center dot OEt(2) and montmorillonite clay are used as catalysts to promote additions. The montmorillonite-catalyzed method in particular is very robust, providing a straightforward and scalable method for the allylation and crotylation of a range of ketones and aldehydes.

• 出版日期2009-6-18