Tolterodine for the treatment of urge urinary incontinence

作者：Elterman Dean S; Chughtai Bilal; Kaplan Steven A; Barkin Jack^*

来源：Expert Opinion on Pharmacotherapy, 2013, 14(14): 1987-1991.

DOI：10.1517/14656566.2013.823158

• Detrol
• incontinence
• overactive bladder
• tolterodine
• urge urinary incontinence

Introduction: Overactive bladder (OAB) and its resultant urge urinary incontinence (UUI) are significant problems that medically, psychologically and financially affect people. The constellation of symptoms comprising OAB affects similar to 16% of the adult population and its prevalence increases with aging. The typical class of medications used to treat OAB is antimuscarinics.
Areas covered: OAB medications, with a focus on tolterodine for the treatment of UUI are reviewed. A thorough review of English language literature using EMBASE/Medline and PubMed has been performed.
Expert opinion: Tolterodine provides a reasonable starting point when treating patients with OAB and UUI. Efficacy and tolerability are generally comparable between tolterodine and other newer antimuscarinics. Tolterodine is a good option as part of the algorithm in the treatment of OAB and UUI.

• 出版日期2013-10