Novel features of early burst suppression predict outcome after birth asphyxia

作者：Iyer Kartik K; Roberts James A; Metsaranta Marjo; Finnigan Simon; Breakspear Michael; Vanhatalo Sampsa^*

来源：Annals of Clinical and Translational Neurology, 2014, 1(3): 209-214.

DOI：10.1002/acn3.32

Burst suppression patterns in the electroencephalogram are a reliable marker of recent severe brain insult. Here we analyze statistical properties of bursts occurring in 20 electroencephalographic recordings acquired from hypothermic asphyxic newborns in the hours immediately following birth. We show that the distributions of burst area and duration in these acute data predict later clinical outcome in both structural neuroimaging and neurodevelopment. Our findings indicate the first early electroencephalographic metrics that offer outcome prediction in asphyxic neonates undergoing hypothermia treatment.

• 出版日期2014-3