A Promising Anticancer and Antimalarial Component from the Leaves of Bidens pilosa

作者：Kumari Priyanka; Misra Kanak; Sisodia Brijesh Singh; Faridi Uzma; Srivastava Suchita; Luqman Suiab; Darokar Mahendra Pandurang; Negi Arvind Singh; Gupta Madan Mohan; Singh Subhash Chandra; Kumar Jonnala Kotesh^*

来源：Planta Medica, 2009, 75(1): 59-61.

DOI：10.1055/s-0028-1088362

• Bidens pilosa
• Asteraceae
• anticancer activity
• antimalarial activity
• phenyl-1,3,5-heptatriyne

Bidens pilosa is used in folk medicine for various applications due to the presence of polyacetylenes, flavonoids, terpenoids, phenylpropanoids and others. Bioactivity-guided fractionation of different extracts of B. pilosa leaf showed potential in vitro anticancer and antimalarial activity and led to the identification of a potential marker Compound, phenyl-1,3,5-heptatriyne. Erythrocyte osmotic fragility experiments revealed the various extracts as well as the marker component's toxicity profiles on normal blood cells.

• 出版日期2009-1