An Expeditious Entry to Benzylic and Allylic Sulfones through Byproduct-Catalyzed Reaction of Alcohols with Sulfinyl Chlorides

作者:Li Hai Hua; Dong De Jun; Jin Yin Huan; Tian Shi Kai*
来源:Journal of Organic Chemistry, 2009, 74(24): 9501-9504.
DOI:10.1021/jo901974h

摘要

In the absence of external catalysts and additives, a broad range of benzylic and allylic alcohols react with various sulfinyl chlorides to afford structurally diversified benzylic and allylic sulfones in moderate to excellent yields, and importantly, a catalysis with byproduct HCl is involved in this new protocol for sulfone synthesis.