A 3-year-old girl with Graves' disease with hypoglycemia following transient adrenal hyporesponsiveness

作者：Satoh Mari^*; Aso Keiko; Ikehara Satoshi; Komine Yumiko; Saji Tsutomu

来源：Journal of Pediatric Endocrinology & Metabolism, 2011, 24(11-12): 1047-1050.

DOI：10.1515/JPEM.2011.307

• adrenal hyporesponsiveness
• hyperthyroidsim
• hypoglycemia

A 3-year-old girl with Graves' disease developed a generalized convulsion as a result of hypoglycemia (25 mg/dL). At the time of the hypoglycemic seizure, her plasma adrenocorticotropin (ACTH) level (1460 pg/mL) was extremely high, but her serum cortisol level (28.4 mu g/dL) was relatively low given the severe stress. The cortisol-releasing hormone (CRH) provocation test done after thyroid function had improved revealed normal ACTH and cortisol responses. Since there was no other cause of hypoglycemia, such as hyperinsulinemia, long-term starvation, suddenly advanced emaciation, or prolonged fasting, it was suspected that the transient adrenal hyporesponsiveness was the main cause of hypoglycemia.

• 出版日期2011-12