A new class of multi-substituted oxazole derivatives: Synthesis and antimicrobial activity

作者:Reddy A Babul; Hymavathi R V; Swamy G Narayana*
来源:Journal of Chemical Sciences, 2013, 125(3): 495-509.
DOI:10.1007/s12039-013-0417-7

摘要

A new and efficient method for the synthesis of multi-substituted oxazole derivatives from various aldehydes has been described. Twenty novel multi-substituted oxazoles containing a heterocyclic moiety were synthesized and evaluated for their antimicrobial activity. The prepared compounds are all reported for the first time and their structures were established by elemental analysis, IR, H-1-NMR, and C-13-NMR and Mass spectra. All the synthesized compounds exhibited in vitro antimicrobial activity.

  • 出版日期2013-5