摘要
A new and efficient method for the synthesis of multi-substituted oxazole derivatives from various aldehydes has been described. Twenty novel multi-substituted oxazoles containing a heterocyclic moiety were synthesized and evaluated for their antimicrobial activity. The prepared compounds are all reported for the first time and their structures were established by elemental analysis, IR, H-1-NMR, and C-13-NMR and Mass spectra. All the synthesized compounds exhibited in vitro antimicrobial activity.
- 出版日期2013-5