A simple synthesis of functionalized 3-methyl-1-pyridinyl-1H-imidazolium salts as bidentate N-heterocyclic-carbene precursors and their application in Ir-catalyzed arene borylation

作者：Peters Martin; Breinbauer Rolf^*

来源：Tetrahedron Letters, 2010, 51(50): 6622-6625.

DOI：10.1016/j.tetlet.2010.10.059

• Borylation
• N-Heterocyclic carbenes (NHC)
• Homogeneous catalysis
• C-H activation
• Bidentate ligands

The selective alkylation of functionalized 2-(1H-imidazol-1-yl)pyridines 1 furnishes 3-methyl-1-pyridinyl-1H-imidazolium salts 2, which can be deprotonated to deliver strongly electron-donating bidentate N-heterocyclic carbene ligands (NHC). The synthesis of these ligands and their application in the iridium-catalyzed C H activated borylation of arenes with its current scope and limitations are reported.

• 出版日期2010-12-15