Anti-TNF alpha therapy may lead to blood pressure reductions through improved endothelium-dependent microvascular function in patients with rheumatoid arthritis

作者：Sandoo A^*; Panoulas V F; Toms T E; Smith J P; Stavropoulos Kalinoglou A; Metsios G S; Gasparyan A Y; Carroll D; van Zanten J J C S Veldhuijzen; Kitas G D

来源：Journal of Human Hypertension, 2011, 25(11): 699-702.

DOI：10.1038/jhh.2011.36

Tumour necrosis factor alpha (TNF-alpha) is a pro-inflammatory cytokine that has a central role in the aetiopathogenesis of rheumatoid arthritis (RA), and may contribute to the development of hypertension. The present longitudinal study examined the effects of anti-TNF alpha treatment on blood pressure (BP) and vascular responses in patients with RA.

• 出版日期2011-11