A facile one-pot synthesis of a fluorescent agarose-O-naphthylacetyl adduct with slow release properties

作者：Kondaveeti Stalin; Chejara Dharmesh R; Siddhanta A K^*

来源：Carbohydrate Polymers, 2013, 98(1): 589-595.

DOI：10.1016/j.carbpol.2013.06.046

• Agarose
• 1-Naphthylacetic acid
• Sustained release property
• Fluorescence

A microwave assisted facile synthesis of a fluorescent 6-O-naphthylacetyl agarose (NA-agarose) employing carbodiimide chemistry (dicyclohexylcarbodiimide/4-dimethylaminopyridine) has been described. NA-agarose was characterized by TGA, GPC, UV spectrophotometry, fluorescence spectroscopy, FT-IR,H-1 and C-13 NMR spectra, exhibiting that in NA-agarose the naphthylacetyl group was attached to the backbone of the agarose polymer. The hydrolysis of NA-agarose in heterogeneous aqueous phase showed that the 1-naphthyl acetic acid (NAA), a plant growth regulator, got released in a controlled manner, the release rate being dependent on the hydrophilicity of the polymer adduct as well as on pH and temperature. The fluorescence emission (lambda(max) 332 nm) of NA-agarose (1 x 10(-3) M) in ethylene glycol was significantly higher (ca. 82%) than that of the molar equivalent of NAA content in the product i.e. 0.08 mg in 1 x 10(-3) M solution. The resulting polymer would be of potential utility as a sustained release plant growth regulator and sensory applications.

• 出版日期2013-10-15
• 单位海洋化工研究院有限公司