科研之友
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摘要
In poor prognosis patients undergoing in vitro fertilization, advance determinations of likely oocyte yields are especially important since oocyte numbers to large degree determine in vitro fertilization cycle outcomes. Based on baseline follicle stimulating hormone and anti-mullerian hormone levels at time of initial presentation, we here, therefore, determined at all ages the probabilities of obtaining 1-aeyen5 oocytes in a retrospective analysis of 1554 consecutive patients undergoing in vitro fertilization cycles at an academically affiliated private fertility center. At lowest levels (aecurrency sign2.5 mIU/mL), Follicle stimulating hormone at all ages was highly predictable for aeyen1 oocyte (88-96 %). Probabilities declined and diverged between ages with increasing follicle stimulating hormone, though narrowed again at high follicle stimulating hormone. Anti-Mullerian hormone demonstrated at higher levels (2.5-aeyen5 ng/ml) at all ages almost perfect probabilities (99-100 %). With declining anti-Mullerian hormone, age categories, however, increasingly diverged, though to lesser degree than follicle stimulating hormone. In poor prognosis patients, follicle stimulating hormone and anti-Mullerian hormone, thus, offer at different ages very specific probabilities for retrieval of 1-aeyen5 oocytes. Since oocyte numbers are associated with embryo numbers, and numbers of transferable embryos with live birth rates, here presented probability tables should facilitate improved prognostication of poor prognosis patients. Discrepancies in here reported probabilities between follicle stimulating hormone and anti-mullerian hormone also further define follicle stimulating hormone and anti-mullerian hormone in their respective abilities to represent functional ovarian reserve at different ages.
- 出版日期2016-11
