A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

作者:El Bakouri Ouissam; Cassu Daniel; Sola Miquel; Parella Teodor; Pla Quintana Anna; Roglans Anna*
来源:Chemical Communications, 2014, 50(59): 8073-8076.
DOI:10.1039/c4cc03190c

摘要

An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0-5 degrees C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations.

  • 出版日期2014