Drug Exposure in Pregnancy and Heart Defects

作者:Matok Ilan; Pupco Anna; Koren Gideon*
来源:Journal of Cardiovascular Pharmacology, 2011, 58(1): 20-24.
DOI:10.1097/FJC.0b013e31821c471b

摘要

Being the most common group of congenital malformations, congenital heart defects have often been investigated to rule out teratogenic effects by medicinal drugs and chemicals. Yet, the use of rigorous epidemiological methods has rejected such claims in many cases. We critically evaluate drugs believed to be associated with an increased risk of causing congenital heart defects, highlighting the debate and the practical implications of such associations.

  • 出版日期2011-7