A new green approach for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-one derivatives using task specific acidic ionic liquid [NMP]H2PO4

作者：Singh Harjinder; Kumari Sudesh; Khurana Jitender M^*

来源：Chinese Chemical Letters, 2014, 25(10): 1336-1340.

DOI：10.1016/j.cclet.2014.05.014

• Benzo[a]xanthenes
• Ionic liquids
• Multicomponent reactions
• Green synthesis

12-Aryl-8,9,10,12-tetrahydrobenzo[a]xanthene-11-one derivatives were synthesized by a convenient and environmentally benign procedure involving multicomponent condensation reactions of substituted aromatic aldehydes with 2,7-dihydroxynaphthalene/2-naphthols/2,6-dihydroxynaphthlene and cyclic 1,3-dicarbonyl compounds in task specific acidic ionic liquid [NMP]H2PO4 at 80 degrees C. This protocol has proved to be efficient in terms of good yields, operational simplicity, easy workup, recyclability of reaction medium/catalyst, and short reaction time.

• 出版日期2014-10