Multi-Stencil Streamline Fast Marching: A General 3-D Framework to Determine Myocardial Thickness and Transmurality in Late Enhancement Images

作者：Merino Caviedes Susana^*; Cordero Grande Lucilio; Revilla Orodea Ana; Sevilla Ruiz Teresa; Teresa Perez M; Martin Fernandez Marcos; Alberola Lopez Carlos

来源：IEEE Transactions on Medical Imaging, 2014, 33(1): 23-37.

DOI：10.1109/TMI.2013.2276765

• Fast marching
• heart
• myocardial viability
• perfusion imaging
• quantification and estimation
• transmurality

We propose a fully 3-D methodology for the computation of myocardial nonviable tissue transmurality in contrast enhanced magnetic resonance images. The outcome is a continuous map defined within the myocardium where not only current state-of-the-art measures of transmurality can be calculated, but also information on the location of nonviable tissue is preserved. The computation is done by means of a partial differential equation framework we have called multi-stencil streamline fast marching. Using it, the myocardial and scarred tissue thickness is simultaneously computed. Experimental results show that the proposed 3-D method allows for the computation of transmurality in myocardial regions where current 2-D methods are not able to as conceived, and it also provides more robust and accurate results in situations where the assumptions on which current 2-D methods are based-i.e., there is a visible endocardial contour and its corresponding epicardial points lie on the same slice-, are not met.

• 出版日期2014-1