Differential impact on acute kidney injury incidence between on- and off pump coronary artery bypass grafting in octogenarians

作者：Spunda Rudolf; Valek Martin; Salmay Myroslav; Prskavec Tomas; Pecha Ondrej; Lindner Jaroslav; Spacek Miroslav^*

来源：Biomedical Papers-Olomouc, 2015, 159(3): 449-454.

DOI：10.5507/bp.2014.023

• acute kidney injury
• coronary artery bypass grafting
• octogenarians

Introduction. Acute kidney injury (AKI) following surgical myocardial revascularization is associated with high mortality and morbidity. The aim of this study was to evaluate the risk of acute kidney injury in a population of very old patients following different surgical techniques.
Patients and Methods. A retrospective study of 310 consecutive patients aged 78 to 93 years, mean 80.5 +/- 2.2, who underwent surgery at one cardiac surgery centre. Based on the surgical technique used the patients were divided into: Group I. CABG (n=134) - surgical myocardial revascularization using extracorporeal circulation and arterial and venous grafts. Group II. OPCABG (n=55) - surgical revascularization without extracorporeal circulation but using arterial and venous grafts. Group III. NOTOUCH (n=121) - no handling with the ascending aorta was performed at all.
Results. A statistically insignificant renoprotective trend was found in patients who underwent surgery without extracorporeal circulation regardless of technique. Comparing groups II and III vs. group I, a significantly poorer renal functioning (median difference in creatinine was 10.0 (32.9) vs 17.5 (35.0), P=0.05) was shown for patients in group I.
Conclusion. Surgical myocardial revascularization without extracorporeal circulation in very old patients is safe. The results of this study show a renoprotective trend.

• 出版日期2015