科研之友
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摘要
The first one pot protocol for the diastereoselective synthesis of oxazolo[2,3-c]isoquinoline was achieved by a metal-free, benzoic acid catalyzed reaction of 1,2,3,4-tetrahydroisoquinoline or trypoline with aldehydes under mild conditions via C-H, C-O bond functionalization. A new approach for the synthesis of highly substituted 1H-pyrrolo[2,1-c][1,4]oxazine was carried out.
- 出版日期2015
