A phase field model for neural cell chemotropism

作者:Najem Sara*; Grant Martin
来源:EPL, 2013, 102(1): 16001.
DOI:10.1209/0295-5075/102/16001

摘要

Chemotropism is the action of targeting a part of the cell by means of chemical mediators and cues, and subsequently delimiting the pathway that it should undertake. hi a, now cell, this initiates axonal elongation. Herein we model this growth, where chemotropic forcing leads the axon, by a phase field method utilizing two dynamical fields assigned respectively to the cell and to its leading edge. Additionally we quantify the condition for the retraction of the axon which takes place when the cell fails to form a synaptic connection.

  • 出版日期2013-4

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