4D radial contrast-enhanced MR angiography with sliding subtraction

作者:Cashen Ty A; Jeong Hyun; Shah Maulin K; Bhatt Hem M; Shin Wanyong; Carr James C; Walker Matthew T; Batjer H Hunt; Carroll Timothy J*
来源:Magnetic Resonance in Medicine, 2007, 58(5): 962-972.
DOI:10.1002/mrm.21364

摘要

A method is presented for high spatial and temporal resolutior 3D contrast-enhanced magnetic resonance angiography. The overall technique involves a set of interrelated component suited to high-frame-rate angiography, including 3D cylindrical k-space sampling, angular undersampling, asymmetric sampling, sliding window reconstruction, pseudorandom view or dering, and a sliding subtraction mask. Computer simulation and volunteer studies demonstrated the utility of each component of the technique. Angiograms of one hemisphere of the intracranial vasculature were acquired with a pixel size of 1.1 x 1.1 x 2.8 mm and a frame rate of 0.35 sec based on a temporal resolution of 3.5 sec. Such a 3D time-resolved, or "4B," tech nique has the potential to noninvasively acquire diagnosti quality images of certain anatomic regions with a frame rat fast enough to not only ensure the capture of an uncontami nated arterial phase, but even demonstrate contrast bolus flow dynamics. Clinical applications include noninvasive imaging of arteriovenous shunting, which is demonstrated with a patient study.