A no-Wnt situation: SFRPs as axon guidance molecules

作者:Drescher U*
来源:Nature Neuroscience, 2005, 8(10): 1281-1282.
DOI:10.1038/nn1005-1281

摘要

SFRPs are endogenous inhibitors of Wnt signaling. New work shows that, independently of its interaction with Wnts, SFRP1 can act as a repulsive guidance molecule for retinal axons on their way to the tectum, signaling through the receptor Fz2.

  • 出版日期2005-10