Allosteric control of nanomechanical DNA origami pinching devices for enhanced target binding

作者:Kuzuya Akinori*; Sakai Yusuke; Yamazaki Takahiro; Xu Yan; Yamanaka Yusei; Ohya Yuichi; Komiyama Makoto*
来源:Chemical Communications, 2017, 53(59): 8276-8279.
DOI:10.1039/c7cc03991c

摘要

Significant enhancement of single-molecular binding to a miRNA target and bidentate and asymmetric conjugation of two distinct thiolated DNA strands to single gold nanoparticles (AuNPs) were visibly demonstrated, by introducing two groups of ligands into our nanomechanical DNA origami devices (DNA pliers) to construct allosterically controllable systems.

  • 出版日期2017-7-28