H3PW12O40 catalyzed synthesis of benzoxazine and quinazoline in aqueous media

作者：Tajbakhsh Mahmood; Hosseinzadeh Rahman; Rezaee Parizad; Tajbakhsh Mahgol

来源：Chinese Journal of Catalysis, 2014, 35(1): 58-65.

DOI：10.1016/S1872-2067(12)60706-2

• Heteropoly acid
• 1,3-Benzoxazine-4-one
• 2-Substituted-quinazolin-4(3H)-one
• 2-Substituted-2,3-dihydroquinazolin-4(1H)-one

A heteropolyacid efficiently catalyzed the cyclocondensation reaction of 2-aminobenzamide and salicylamide with aldehydes and ketones to afford good yields of benzoxazine and quinazoline ring systems in an aqueous medium. The method gives clean reactions, has simple workup procedure, and uses environment friendly conditions.

• 出版日期2014-1