摘要
1,3-Dipolar cycloaddition of N-aryl-C-(2,2-dichloro-1-phenylcyclopropyl)nitrones to N-arylmaleimides stereoselectively gives substituted pyrrolo[3,4-d]isoxazolidines as mixtures of two diastereoisomers differing by configuration at the C(1') atom of the cyclopropane ring in the substituent on C(3). Substituents in the aromatic rings of the initial nitrone and maleimide do not affect the stereochemistry of the process.
- 出版日期2011-1