An efficient polymer-supported copper(II) catalyst for the N-arylation reaction of N(H)-heterocycles with aryl halides as well as arylboronic acids

作者：Islam Manirul^*; Mondal Sanchita; Mondal Paramita; Roy Anupam Singha; Tuhina Kazi; Salam Noor; Paul Sumantra; Hossain Dildar; Mobarok Manir

来源：Transition Metal Chemistry, 2011, 36(4): 447-458.

DOI：10.1007/s11243-011-9489-8

Immobilization of copper onto polystyrene provided a polymer-supported copper(II) catalyst, which was effective in cross-coupling reactions between N-containing substrates and arylboronic acids using methanol as a solvent in air under base-free conditions. This catalyst was also effective in N-arylation of imidazole with aryl halides in DMSO using K(2)CO(3) as a base under nitrogen atmosphere. The catalyst was characterized by physicochemical and spectroscopic techniques. The product N-arylimidazoles and N-arylbenzimidazoles were isolated in good to excellent yields. This copper catalyst was air stable and could be recycled with minimal loss of activity.

• 出版日期2011-5