A novel hydrazide type organocatalyst for enantioselective Diels-Alder reactions

作者:Suzuki Ichiro*; Ando Masafumi; Shimabara Rumiko; Hirata Ai; Takeda Kei
来源:Organic and Biomolecular Chemistry, 2011, 9(8): 3033-3040.
DOI:10.1039/c0ob01138j

摘要

The development of a new class of hydrazide type organocatalyst, (4R, 5R)-1,3-bis(isopropylamino)4,5- dihenylimidazolidin-2-one 2a, for enantioselective Diels-Alder reactions between cyclopentadiene and alpha,beta-unsaturated aldehydes are presented. The new organocatalyst 2a promoted the reaction, affording Diels-Alder adducts in good yields with good levels of enantioselectivity.

  • 出版日期2011