A simple recipe for direct writing complex 45S5 Bioglass (R) 3D scaffolds

作者：Eqtesadi Siamak; Motealleh Azadeh; Miranda Pedro^*; Lemos Alexandra; Rebelo Avito; Ferreira Jose M F

来源：Materials Letters, 2013, 93: 68-71.

DOI：10.1016/j.matlet.2012.11.043

• 45S5 Bioactive glass
• Robocasting
• Direct-writing
• Carboxymethyl cellulose

Direct-writing fabrication techniques, such as robocasting, have been ignored up to date for the production of scaffolds from 45S5 Bioglass (R), probably due to difficulties in the preparation of stable high solids loading colloidal suspensions (inks) from 45S5 Bioglass (R) powders using traditional approaches. Here, we report how these difficulties can be overcome. Aqueous suspensions containing 45 vol% of 45S5 Bioglass (R) were successfully prepared using carboxymethyl cellulose (CMC) as single multifunctional (dispersant, binder, gelation agent) processing additive. Playing with the molecular weight (MW) and amount of CMC enabled tuning the theological properties of the inks to meet the stringent requirements of robocasting. An incomplete surface coverage allowing bridging flocculation to occur is the key to obtain highly performing inks.

• 出版日期2013-2-15