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摘要
Purpose To assess the prevalence of astigmatism and its relationship with biometric optic components in preterm school children with diode laser-treated threshold retinopathy of prematurity (ROP). %26lt;br%26gt;Methods A prospective, cross-sectional study in which cycloplegic keratometry, refraction, and ultrasound biometric measurement of optic components were performed on 24 consecutive preterm children with diode laser-treated threshold ROP at the age of 9 years. The study results were compared with data on 1021 age-matched full-term control children from a national survey. %26lt;br%26gt;Results The laser-treated eyes had a mean astigmatism of 3.47 D, with a mean spherical equivalent of -4.49 D. Of the 46 eyes studied, 98% of eyes showed astigmatism %26gt;= 0.5D and 50% had high astigmatism (%26gt;3.0 D). Most astigmatic eyes (97.7%) showed with-the-rule astigmatism, with the mean plus cylinder axis at 89.30 degrees. Further correlation analysis showed the astigmatism in refraction was highly correlated with the corneal astigmatism (r = 0.921, P%26lt;0.001) and the vertical corneal curvature (r = 0.405, P = 0.005). There was significantly steeper vertical corneal curvature (P = 0.003) and flatter horizontal corneal curvature (P = 0.031) in eyes with laser-treated ROP when compared with age-matched full-term controls. The eyes with laser-treated ROP also show significantly thicker lens (3.93mm) and shallower anterior chamber depth (ACD; 2.92mm) than full-term controls (P%26lt;0.001). %26lt;br%26gt;Conclusions There is significantly higher prevalence and greater magnitude of astigmatism in eyes with laser-treated threshold ROP compared with full-term controls. The steeper vertical corneal curvature component contributes to the increased astigmatism in eyes with laser-treated ROP. Eye (2013) 27, 374-381; doi:10.1038/eye.2012.263; published online 7 December 2012
- 出版日期2013-3
