Novel PAMs Targeting NMDAR GluN2A Subunit

作者：Xiang Zixiu; Conn P Jeffrey^*

来源：Neuron, 2016, 89(5): 884-886.

DOI：10.1016/j.neuron.2016.02.025

In this issue of Neuron, Hackos et al. (2016) report the discovery of novel positive allosteric modulators that are highly selective for GluN2A-containing NMDA receptors. This novel class of PAMs shows distinct effects on synaptic plasticity.

• 出版日期2016-3-2