Development of a CFD Model of Bubble Column Bioreactors: Part One - A Detailed Experimental Study

作者:McClure Dale D; Kavanagh John M; Fletcher David F*; Barton Geoffrey W
来源:Chemical Engineering & Technology, 2013, 36(12): 2065-2070.
DOI:10.1002/ceat.201300544

摘要

The holdup and bubble size distribution (BSD) in bubble columns using both air/water and an industrially relevant air/fermentation media system are investigated. It was found that the BSD in the air/fermentation media system was quite narrow and did not change with height. In contrast, the BSD in the air/water system varied considerably with height depending on the sparger design used. Holdup measurements were also performed for different superficial velocities. The holdup in the air/fermentation media system was greater than that for the air/water system, a result attributed to the presence of surface-active compounds in the fermentation media.

  • 出版日期2013-12