AN ELECTROCHEMICAL SENSOR FOR L-TRYPTOPHAN USING A MOLECULARLY IMPRINTED POLYMER FILM PRODUCED BY COPOLYMERIZATION OF o-PHENYLENEDIAMINE AND HYDROQUINONE

作者：Zhao, Fan; Li, Xiao^*; Xu, Wen; Zhang, Weiying; Ying, Xiaoguang

来源：Analytical Letters, 2014, 47(10): 1712-1725.

DOI：10.1080/00032719.2014.880172

• Electrochemical sensor
• Electropolymerization
• Hydroquinone
• L-tryptophan
• Molecularly imprinted film
• O-phenylenediamine

An electrochemical sensor for L-tryptophan based on a molecularly imprinted polymer was developed. The sensing film was prepared by the co-electropolymerization of o-phenylenediamine and hydroquinone on a gold electrode in the presence of L-tryptophan as the template. The performance of the L-tryptophan sensor was characterized by cyclic voltammetry, differential pulse voltammetry, and alternating current impedance. Under the optimal experimental conditions, the relative current change was linear to the concentration of L-tryptophan in the range of 1.0 x 10(-8) to 1.0 x 10(-6) mol/L and a detection limit of 0.50 x 10(-8) mol/L was obtained. The sensor showed high sensitivity and selectivity for L-tryptophan. The imprinting factor was 3.58 and selectivity factors of L-tryptophan compared to analogs were larger than 2. The sensor also demonstrated good resistance to acidic, basic, and organic environments.

• 出版日期2014
• 单位福州大学