A novel spinosin derivative from Semen Ziziphi Spinosae

作者:Xie, Yuan-Yuan; Xu, Zhi-Lin; Wang, Hui; Kano, Yoshihiro; Yuan, Dan*
来源:Journal of Asian Natural Products Research, 2011, 13(12): 1151-1157.
DOI:10.1080/10286020.2011.623128

摘要

A novel spinosin derivative, 6'''-(4''''-O-beta-D-glucopyranosyl)-vanilloyl spinosin (1) was isolated from the methanol extract of Semen Ziziphi Spinosae, together with five known flavonoids, swertish (2), spinosin (3), 6'''-feruloylspinosin (4), isospinosin (5) and kaempferol 3-O-a-L-rhamnopyranosyl-(1 -> 2)-O-[O-alpha-L-rhamnopyranosyl-(1 -> 6)]-beta-D-glucopyranoside (6), and two alkanoids, zizyphusine (7) and 6-(2',3'-dihydroxyl-4'-hydroxymethyl-tetrahydro-furan-1'-yl)-cyclopentene[c]pyrrole-1,3-diol (8). The structure of compound 1 was elucidated by spectroscopic methods including UV, IR, ESI-TOF-MS, 1D, and 2D NMR techniques.