A practical two-step synthesis of imidazo[1,2-a]pyridines from N-(prop-2-yn-1-yl)pyridin-2-amines

作者：Sucunza David; Samadi Abdelouahid; Chioua Mourad; Silva Daniel B; Yunta Cristina; Infantes Lourdes; Carmo Carreiras M; Soriano Elena; Marco Contelles Jose^*

来源：Chemical communications, 2011, 47(17): 5043-5045.

DOI：10.1039/c1cc10641d

The Sandmeyer reaction of differently C-2 substituted N-(prop-2yn-1-ylamino)pyridines is an efficient, mild, new and practical method for the stereospecific synthesis of (E)-exo-halomethylene bicyclic pyridones bearing the imidazo[1,2-a]pyridine heterocyclic ring system.

• 出版日期2011
• 单位河北医科大学