Anti-integrin and integrin detection using the heat dissipation of surface plasmon resonance

作者:Huang Hao Ting*; Huang Chen Yu; Ger Tzong Rong; Wei Zung Hang
来源:Applied Physics Letters, 2013, 102(11): 111109.
DOI:10.1063/1.4798276

摘要

We verified that the heat dissipation of surface plasmon resonance can be measured using photothermal deflection method. The maximum value of photothermal deflection corresponded to the occurrence of surface plasmon resonance. The detection of anti-integrin and integrin biomolecules that exhibit specific binding was demonstrated using this technique. From our experimental results it shows that the photothermal deflection method can be used to obtain the surface plasmon resonance angles and angle shift.