Antifungal sesquiterpenoids from Chloranthus japonicus

作者:Li, Xu-Hong; Yan, Huan; Ni, Wei; Qin, Xu-Jie; Zhao, Qing; Ji, Zhi-Qin; Liu, Hai-Yang*
来源:Phytochemistry Letters, 2016, 15: 199-203.
DOI:10.1016/j.phytol.2016.01.005

摘要

Two new eudesmane-type sesquiterpenoids, chlojaponols A (1) and B (2), and four new lindenane-type sesquiterpenoid lactones, chlojaponilactones F-I (3-6), along with six known analogues were isolated from whole plants of Chloranthus japonicus. The structures of new compounds were established based on analyses of spectroscopic data including HR-MS, D-1 and D-2 NMR. The antifungal activities of some of the compounds were tested and compound 5 showed 82.61% inhibition to Sclerotinia sclerotiorumat the concentration of 50 mu g/mL.