A new cause of false positive voriconazole levels: Watch your collection tubes !

作者：Burillo Almudena; Gomez Lopez Alicia; Escribano Pilar; Galar Alicia; Salinas Beatriz; Diaz Perez Nadire; Munoz Patricia; Bouza Emilio

来源：Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2018, 1092: 328-331.

DOI：10.1016/j.jchromb.2018.06.022

• Voriconazole
• Therapeutic drug monitoring
• Chromatography
• High-pressure liquid
• Clinical laboratory techniques
• Data accuracy

We communicate the interference of a compound of the blood collection tube with the accuracy of a validated high-pressure liquid chromatography method with ultraviolet detection for quantifying voriconazole levels, which led to false positive results. This could have serious consequences for patient management. Our advice is to implement external assessment programs.

• 出版日期2018-8-15