摘要

A simple and efficient one-pot synthesis of 2,3-disubstituted isoindolinones via the reaction of o-lithiated aromatic imines with carbon monoxide under one atmospheric pressure has been developed. Preliminary in vitro tests for fungicidal activity of these isoindolinone derivatives have been carried out, indicating that most of them exhibit good fungicidal activities.

  • 出版日期2015-10-7
  • 单位元素有机化学国家重点实验室; 南开大学