Association models for binding of molecules to nanostructures

作者:Ahumada Manuel; Lissi Eduardo; Montagut Ana Maria; Valenzuela Henriquez Francisco; L Pacioni Natalia; Alarcon Emilio I*
来源:Analyst, 2017, 142(12): 2067-2089.
DOI:10.1039/c7an00288b

摘要

The interaction between nanoparticles and molecules plays a key role in determining the activity and performance of a given nanostructure. These interactions are pivotal for a variety of applications including drug delivery, surface manipulation for targeted therapies, and catalysis. However, to this day, gathering precise association parameters for the interaction of the molecules with nanostructures remains elusive and mostly imprecise. In this review, we present a critical discussion of the most commonly used techniques and models intended for determining the association of molecules with nanoparticles. Particular emphasis has been put on discussing the limitations and pitfalls related to determining association constants in this tutorial review.

  • 出版日期2017-6-21