A conjugated polymer-peptide hybrid system for prostate-specific antigen (PSA) detection

作者:Lee Kangwon; Mandal Suparna; Morry Jinga; Srivannavit Onnop; Gulari Erdogan; Kim Jinsang*
来源:Chemical communications, 2013, 49(40): 4528-4530.
DOI:10.1039/c3cc00280b

摘要

We developed fast and readily applicable microarray chips to detect PSA by designing a novel conjugated polymer (energy donor) and combining it with on-chip peptide synthesis. The selective cleavage of a probing peptide labelled with a dye or a quencher (energy acceptor) produced a fluorescence sensory signal via fluorescent energy resonance transfer (FRET).

  • 出版日期2013