A Hybrid Coumarin-Semifluorescein-Based Fluorescent Probe for the Detection of Cysteine

作者：Jia, Xuhong; Niu, Changhe; He, Yuanhua^*; Sun, Yuanchao; Liu, Heng^*

来源：Journal of Fluorescence, 2018, 28(5): 1059-1064.

DOI：10.1007/s10895-018-2269-5

• Turn-on fluorescent probe
• Cysteine detection
• Cell imaging

A new type of turn-on fluorescent probe CF-AC for the detection of Cys was firstly reported. The probe exhibited an excellent response to Cys with high selectively and sensitivity. In the presence of Cys, two fluorescence emission peaks at 525 nm and 650 nm appeared accompanied by the fluorescence color change from blue to red. Morever, the probe had good biocompatibility and could be successfully used for fluorescence imaging of Cys in MCF-7 cells.

• 出版日期2018-9
• 单位中国民用航空飞行学院; 华中科技大学; 湖北大学