科研之友
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摘要
Glycine, as a kind of commercially available and inexpensive ligand, is used to prepare an air-stable and water-soluble catalyst used in Sonogashira reaction in our study. In the presence of 1% [PdCl2(NH2CH2COOH)(2)] as catalyst, excellent catalytic activity towards the Sonogashira coupling of aryl iodides with terminal alkynes without using any additive such as Cu(I)-cocatalyst is observed in a mixture of water and acetone (3/3mL) under air at 60 degrees C with NaOH as a base, giving products in good to excellent yields.
- 出版日期2015
- 单位宜春学院
