Neopentylglycolborylation of Aryl Mesylates and Tosylates Catalyzed by Ni-Based Mixed-Ligand Systems Activated with Zn

作者:Wilson Daniela A; Wilson Christopher J; Moldoveanu Costel; Resmerita Ana Maria; Corcoran Patrick; Hoang Lisa M; Rosen Brad M; Percec Virgil*
来源:Journal of the American Chemical Society, 2010, 132(6): 1800-+.
DOI:10.1021/ja910808x

摘要

The mixed-ligand system NiCl2(dppp)/dppf is shown to be an effective catalyst for the neopentylglycolborylation of ortho-, meta-, and para- substituted electron-rich and electron-deficient aryl mesylates and tosylates. The addition of Zn powder as a reductant dramatically increases the reaction yield and reduces the reaction time by more than an order of magnitude, providing complete conversion in 1-3 h

  • 出版日期2010-2-17