A new and general one-pot synthesis of propargyl alcohols from esters

作者:Chae Min Jung; Jeon Ah Ram; Livinghouse Tom; An Duk Keun*
来源:Chemical communications, 2011, 47(11): 3281-3283.
DOI:10.1039/c0cc04597g

摘要

Intermediates easily prepared by partial reduction of various esters with LDBBA as a reducing agent smoothly react with lithium acetylides to give propargyl alcohols, without isolation of partial reduction intermediates, in good yields (73-83%).

  • 出版日期2011