An Efficient and Facile Synthesis of Iminoquinazolinedione Derivatives by Solid-State Diels-Alder Reaction under Catalyst-Free Conditions

作者：Sarmah Manas M; Bhuyan Debajyoti; Prajapati Dipak^*

来源：Synlett, 2013, 24(13): 1667-1670.

DOI：10.1055/s-0033-1339296

• atom economy
• solid-state Diels-Alder reaction
• iminoquinazoline-2,4-dione
• green alternative

A solvent-and catalyst-free Diels-Alder reaction with 6-(2-morpholinovinyl)-1,3-dimethyluracil, cinnamaldehyde, and an amine has been developed for the construction of iminoquinazoline-2,4-dione derivatives within a short reaction time. The method is clean, simple, and operation friendly.

• 出版日期2013-8